This position is designed for an individual to participate in National Toxicology Program (NTP) and National Institute of Environmental Health Sciences (NIEHS) research projects, work to achieve accuracy of NTP pathology data, learn rodent pathology, and continue education towards achievement of board certification by the ACVP (Clinical or Anatomic pathology). At least one year, and preferably two years, of pathology residency training is required. The research performed can be thesis work in a graduate program toward the achievement of a PhD degree by arrangement with various universities.

The post-doctoral fellow will work with an NTP Study Pathologist to learn duties related to ensuring that pathology data generated in an assigned Toxicology/Carcinogenesis study are accurate, consistent, and appropriately reported. The person will also be involved in the design and review of protocols for study of specific chemicals/agents for the NTP as well as being a Pathology Working Group (PWG) member to evaluate and correct discrepancies within the pathology data of particular studies. The fellow will be closely involved in collaborative research and pathology support for NTP-sponsored initiatives and NIEHS intramural research investigators. Some of the projects are relevant to current NTP initiatives such as phenotypic anchoring of pathology with toxicogenomics findings, toxicity of dioxins, and other collaborative research efforts designed to understand the biology and public health relevance of toxic and carcinogenic endpoints. Some of the efforts will be in learning fundamental and toxicologic pathology in preparation for board certifying examination in veterinary pathology. We have a partnership with the pathology residency program at nearby North Carolina State University, College of Veterinary Medicine for access to training resources and participation in pathology conferences and rounds. Service in surgical or necropsy pathology can also be arranged in some circumstances.

The NIEHS employs at least 10 veterinary pathologists, working in areas of toxicologic pathology and research. Research projects are ongoing in areas of molecular carcinogenesis, toxicological pathology, toxicogenomics utilizing investigative techniques such as microarray gene expression analysis, real time RT-PCR, magnetic resonance imagery (MRI) microscopy, in situ hybridization, electron microscopy, and immunohistochemistry. The Research Triangle Park area is home to more than 70 veterinary pathologists who are employed at various institutions including academia (such as University of North Carolina, North Carolina State University, and Duke University), private industry (GlaxoSmithKline, Experimental Pathology Laboratories, Pathology Associates International/ Charles River Labs, and Integrated Laboratory Services), veterinary diagnostic laboratories (Rollins Animal Disease Diagnostic Labs and Antech Diagnostics), and other government agencies (such as the Environmental Protection Agency). In addition, the NIEHS has a strong program in laboratory animal medicine with five board certified (ACLAM) laboratory animal veterinarians and a recently established National Center for Toxicogenomics.

Some relevant web sites are:

National Toxicology Program - http://ntp-server.niehs.nih.gov/
Laboratory of Experimental Pathology - http://dir.niehs.nih.gov/dirlep/
National Center for Toxicogenomics - http://www.niehs.nih.gov/nct/

Contact information can be obtained from:

David E. Malarkey DVM, PhD, DACVP
Head, National Toxicology Program Pathology Group
Laboratory of Experimental Pathology - Maildrop B3-06
National Institute of Environmental Health Sciences
111 Alexander Dr.
P0 Box 12233
Research Triangle Park, NC 27709

phone:(919) 541-1745
fax: (919) 541-7666
email: malarkey@niehs.nih.gov

Return to directory listing

. . . . . . . . .

ACVP HOME | About ACVP | Annual Meeting | Calendar of Events | News & Public Relations | Student Chapters | Training & Education | Certifying Exam | Other Links | Career Opportunities | Members Only | Contact Us

Copyright © 2009, American College of Veterinary Pathologists. All rights reserved.